Information from the Human Genome Project has scientists examining the role of genetics and other risk factors involved in the development of disease. Understanding this complex interplay of genetics and environment will lead us to new methods of disease detection and prevention.

The concept of “bio chemical individuality” first proposed in 1956, explains variability in disease, susceptibility, nutrient needs and drug responsiveness.

People are as different on the inside as they are on the outside.

Genomics – Study of totality of genetic code of a single species.
The human genome consists of slightly more than 3,000,000,000 nucleotides and it codes for every protein and every enzyme made by the human body.

Gene / Environment Interaction
Virtually all human diseases result from the interaction of genetic susceptibility factors and modifiable environmental factors, broadly defined to include infectious, chemical, physical, nutritional and behavioral factors. This is perhaps the most important fact in understanding the role of genetics and environment in the development of disease.

Genetic Susceptibility and Risk
The specter of genetic determinism looms large in the public consciousness; most people are convinced that our genes are our fate. Nothing could be further from the truth. In fact, phenotypic expression of genomic determinants is largely modifiable. It is becoming increasingly evident that who we are as individuals is a function of both our genetic make up and the environment to which we subject our genes and our bodies.

“SNPS” – Single Nucleotide Polymorphisms
To date, roughly 100,000 SNP’s (pronounced snips) have been identified and literally millions exist in the DNA, but the vast majority of these have no impact on human physiology. Finding the polymorphisms that make a real difference in our physiology is the first task of predictive genomics.

Predictive Genomics
To be of clinical importance, the polymorphisms identified in predictive genomic testing must meet four criteria. They must be, 1. Relevant 2. Prevalent 3. Modifiable 4. Measurable

Functional Integrity = Balance = Health
Diet, nutrition and lifestyle factors can exert an enormous influence on how, or even if, a gene will express itself. Knowing about increased risk is a first step towards a committed and effective prevention strategy.

Lee Raymond Light, M.D. Naples Longevity Clinic 239-659-3266 or 239-262-1833 850 Central Ave. #301 - Naples, FL 34102
Board Certified Internal Medicine, Geriatrics and the American Academy of Anti-Aging Medicine (Bioidentical Hormones)
Conveniently located in S.W. Florida